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Discrete mutations introduced in the predicted nucleotide-binding sites of the mdr1 gene abolish its ability to confer multidrug resistanceAZZARIA, M; SCHURR, E; GROS, P et al.Molecular and cellular biology (Print). 1989, Vol 9, Num 12, pp 5289-5297, issn 0270-7306, 9 p.Article

The chemistry of methotrexate and its analoguesRAHMAN, L. K. A; SIRI RAM CHANDRA.Medicinal research reviews (Print). 1988, Vol 8, Num 1, pp 95-155, issn 0198-6325Article

Structure-function analysis of thin filament proteins expressed in Escherichia coliHITCHCOCK-DEGREGORI, S. E.Cell motility and the cytoskeleton. 1989, Vol 14, Num 1, pp 12-20, issn 0886-1544, 9 p.Article

On a fragment approach to structure-activity correlationsRANDIC, M; JURS, P. C.Quantitative structure-activity relationships. 1989, Vol 8, Num 1, pp 39-48, issn 0931-8771, 10 p.Article

Colchicine and its analogues: recent findingsBROSSI, A; YEH, H. J. C; CHRZANOWSKA, M et al.Medicinal research reviews (Print). 1988, Vol 8, Num 1, pp 77-94, issn 0198-6325Article

Rationalizing Three-Dimensional Activity Landscapes and the Influence of Molecular Representations on Landscape Topology and the Formation of Activity CliffsPELTASON, Lisa; IYER, Preeti; BAJORATH, Jürgen et al.Journal of chemical information and modeling. 2010, Vol 50, Num 6, pp 1021-1033, issn 1549-9596, 13 p.Article

Structure-activity relationships of aminocoumarin-type gyrase and topoisomerase IV inhibitors obtained by combinatorial biosynthesisFLATMAN, Ruth H; EUSTAQUIO, Alessandra; LI, Shu-Ming et al.Antimicrobial agents and chemotherapy. 2006, Vol 50, Num 4, pp 1136-1142, issn 0066-4804, 7 p.Article

A strategy for ranking environmentally occurring chemicals. VI: QSARs for the mutagenic effects of halogenated aliphaticsERIKSSON, L; HELLBERG, S; JOHANSSON, E et al.Acta chemica scandinavica (Copenhagen. 1989). 1991, Vol 45, Num 9, pp 935-944, issn 0904-213XArticle

Selective and efficient syntheses of phototoxic 2,2':5',2''-terthiophene derivatives bearing a functional substituent in the 3'- or the 5-positionROSSI, R; CARPITA, A; CIOFALO, M et al.Tetrahedron (Oxford. Print). 1991, Vol 47, Num 39, pp 8443-8460, issn 0040-4020Article

La thrombomoduline : un nouveau protéoglycanne relation structure-fonction = Thrombomodulin: a new proteoglycanBOURIN, M. C.Annales de biologie clinique (Paris). 1991, Vol 49, Num 4, pp 199-207, issn 0003-3898Article

Anti-fluorescein antibodies as structure-function models to examine fundamental immunochemical and spectroscopic principlesVOSS, E. W.Comments on molecular and cellular biophysics. 1990, Vol 6, Num 4, pp 197-221, issn 0143-8123, 25 p.Article

Influence of neurophysin residues 1-8 on the optical activity of neurophysin-peptide complexes. Direct evidence that the 1-8 sequence alters the environment of bound peptideBRESLOW, E; CO, R. T; HANNA, P et al.International journal of peptide & protein research. 1989, Vol 34, Num 1, pp 21-27, issn 0367-8377Article

Somatostatin rand analogs lack splanchnic vasoconstrictive effects in anesthetized pigsCAMBRIA, R. P; NEVILLE, R; BALLANTYNE, G. H et al.The Journal of surgical research. 1987, Vol 43, Num 5, pp 452-459, issn 0022-4804Article

Aspects of the antituberculous activity of 27753-RP, a new semisynthetic derivative of griselimycineTOYOHARA, M.Annales de l'Institut Pasteur. Microbiologie. 1987, Vol 138, Num 6, pp 737-744, issn 0769-2609Article

Investigation of Structure-Activity Relationships of Oxyntomodulin (Oxm) Using Oxm AnalogsDRUCE, Maralyn R; MINNION, James S; FIELD, Benjamin C. T et al.Endocrinology (Philadelphia). 2009, Vol 150, Num 4, pp 1712-1721, issn 0013-7227, 10 p.Article

Navigating structure-activity IandscapesBAJORATH, Jürgen; PELTASON, Lisa; WAWER, Mathias et al.Drug discovery today. 2009, Vol 14, Num 13-14, pp 698-705, issn 1359-6446, 8 p.Article

Actin structure-function relationships in vitro using oligodeoxynucleotide-directed site-specific mutagenesisRUBENSTEIN, P. A; SOLOMON, L. R; SOLOMON, T et al.Cell motility and the cytoskeleton. 1989, Vol 14, Num 1, pp 35-39, issn 0886-1544, 5 p.Article

Synthesis and antihypertensive activity of some S-substituted 4H-1,2,4-triazolesEMILSSON, H; SELANDER, H; GAARDNER, J et al.Acta pharmaceutica suecica. 1987, Vol 24, Num 3, pp 123-134, issn 0001-6675Article

Quantum pharmacologic studies applicable to the design of anticonvulsants : theoretical conformational analysis and structure-activity studies of barbituratesBIKKER, J. A; KUBANEK, J; WEAVER, D. F et al.Epilepsia (Copenhagen). 1994, Vol 35, Num 2, pp 411-425, issn 0013-9580Article

Correlation between biological activity and the structure of 6-amino-2-R-thiobenzothiazoles. Anti-yeast activity and inhibition of photochemical activity of chloroplastsKRALOVA, K; BUJDAKOVA, H; KUCHTA, T et al.Pharmazie. 1994, Vol 49, Num 6, pp 460-461, issn 0031-7144Article

Design of novel antiestrogensHENDRY, L. B; CHU, C. K; ROSSER, M. L et al.Journal of steroid biochemistry and molecular biology. 1994, Vol 49, Num 4-6, pp 269-280, issn 0960-0760Conference Paper

Glucocorticoid antagonistsAGARWAL, M. K; HAINQUE, B; MOUSTAID, N et al.FEBS letters. 1987, Vol 217, Num 2, pp 221-226, issn 0014-5793Article

SAR Maps : A New SAR Visualization Technique for Medicinal ChemistsAGRAFIOTIS, Dimitris K; SHEMANAREV, Maxim; CONNOLLY, Peter J et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 24, pp 5926-5937, issn 0022-2623, 12 p.Article

Synthesis and insecticidal activity of 1,3-dithianesMITSUDERA, H; KONISHI, K.Nippon Noyaku Gakkaishi. 1991, Vol 16, Num 3, pp 387-395, issn 0385-1559Article

Validation of QSAR'sWOLD, S.Quantitative structure-activity relationships. 1991, Vol 10, Num 3, pp 191-193, issn 0931-8771Article

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